•The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults
In this clinical study, NMN significantly increased concentrationsNAD+in the blood, improved performance in the six-minute walk test, and was well tolerated without serious side effects.Link to the study
•Long-term NMN treatment increases lifespan and health span in mice
Chronic supplementation with NMN in mice delayed frailty, improved metabolic health, and extended lifespan, with no detectable toxic effects.Link to the study
•Nicotinamide mononucleotide improves spermatogenic function in diabetic mice
Oral administration of NMN increased sperm count, improved testicular structure, and reduced abnormal sperm counts in diabetic mice.Link to the study
•Supplementing Boar Diet with Nicotinamide Mononucleotide improves semen quality
NMN supplementation in boars increased ejaculate volume, sperm density and motility, reduced abnormalities and increased serum testosterone levels.Link to the study
•Resveratrol prolongs lifespan and improves health in mice on a high-calorie diet
A classic Harvard study (Baur et al., 2006) showed that resveratrol extended the lifespan of mice fed a high-calorie diet, improved insulin sensitivity, reduced inflammation, and protected heart function.Link to the study
•Resveratrol improves mitochondrial function and protects against metabolic diseases by activating SIRT1 and PGC-1α
A study in the journal *Cell* (Lagouge et al., 2006) proved that resveratrol activates the SIRT1 and PGC-1α pathways, increases mitochondrial density and energy expenditure, which contributes to metabolic health and resistance to obesity.Link to the study
•Resveratrol supplementation induces browning of white adipose tissue and metabolic benefits in humans
In a double-blind human study, daily supplementation with resveratrol stimulated the browning of white adipose tissue and increased energy expenditure, indicating the possibility of body mass control through mitochondrial activation.Link to the study
•Resveratrol activates SIRT1 in vivo and improves muscle mitochondrial function in humans with type 2 diabetes
In patients with type 2 diabetes, resveratrol activated SIRT1, improved mitochondrial oxidation in muscle, and reduced oxidative stress, confirming its effect on energy and metabolic resilience.Link to the study