Resveratrol - the secret of red wine for the heart, brain and longevity

Resveratrol is a polyphenol produced by plants in response to stress. It is most abundant in the skin of grapes and red wine, but also in Japanese gorse (Polygonum cuspidatum) – a standard source of highly pure trans-resveratrol in supplements.

This connection is connected with the so-called the "French paradox" - a lower rate of cardiovascular disease despite dietary fat - attributed to regular consumption of red wine and the presence of polyphenols such as resveratrol.

What do the studies say?

• Cerebral circulation and focus: 250–500 mg of trans-resveratrol increased cerebral blood flow during mental performance in a double-blind study (Kennedy et al., 2010). Study
• Support for the cardiovascular system: 10 mg daily for 3 months in patients with a history of infarction improved left ventricular function , endothelial function and reduced LDL (Magyar et al., 2012). Study
• Effects similar to caloric restriction: 150 mg daily for 30 days in obese subjects induced favorable metabolic changes related to energy and metabolism (Timmers et al., 2011). Study

Dosage and notes

Recommendations on the market often go up to 500 mg per day of trans-resveratrol, and much higher doses of up to 1000 mg per day have been tested in clinical studies.

Note: not for pregnant women, nursing mothers, children and people hypersensitive to the ingredient. Do not exceed the recommended dose. A nutritional supplement is not a substitute for a varied diet.

Resveratrol from Japanese knotweed provides clear scientific support for brain circulation, cardiovascular health and metabolic profile. With thoughtful dosing and a healthy lifestyle, it makes a meaningful addition to your longevity routine.

References: Kennedy DO et al., 2010; Magyar K et al., 2012; Timmers S et al., 2011 (links in text).